Copyright 2021 © University of Southampton Page 1 of 4 UNIVERSITY OF SOUTHAMPTON ELEC6213W1 SEMESTER 2 FURTHER ASSESSMENT 2020-21 IMAGE PROCESSING This paper contains 1 question with 8 sub questions Answer All sub questions. An outline marking scheme is shown in brackets to the right of each question. ELEC6213W1 Copyright 2021 © University of Southampton Page 2 of 4 Hypoxic Ischemic Encephalopathy (HIE) is a disease caused by the shortage of oxygen during birth. In order to check if a new born baby is affected by HIE, MRI scans of the brain are taken after the birth. Figure (1) shows MRI scans of four patients affected by HIE. This figure shows the MRI scans of the affected infant brains in the order of HIE severity by depicting a healthy brain in figure (1.A), the least affected brain in figure (1.B) and finally the most affected brain in figure (1.D). As observed from these MR images, brain vessels become more distinctive and apparent in MRI scans as HIE becomes more severe. We have a small dataset of these MRI scans and you are tasked to analyse these images. Figure 1 (i) Advance an algorithm to detect vessels in these MRI scans. [10 marks] (ii) In the presence of noise, explain what you can do to minimise the effects of noise in these images [5 marks] ELEC6213W1 Copyright 2021 © University of Southampton Page 3 of 4 (iii) Propose an algorithm to detect the vertical central line separating the two halves of the brain and remove that line in order to make sure that the vertical central line is not considered as a vessel in the feature extraction step. Explain how your method works. [10 marks] (iv) Propose features which can be extracted from these images to classify these images in four groups. (i.e., Group A: Healthy brains, Groups B, mildly HIE brains, Group C: Moderate HIE brains, and Group D: Severe HIE brains) [15 marks] (v) Explain what the accuracy is for each group, if a classifier (random classifier) randomly assigns an MRI scan to a group (assume each group contains 10 patients). However our dataset is not balanced. This means that there are 100 healthy brains in group A and groups B, C and D each have 10 HIE brains. Find the accuracy of a random classifier for this unbalanced dataset. Describe a scenario where this unbalance dataset can produce a total accuracy of more than 76% for even a very bad classifier which assigns all images to only one of the groups. [15 marks] (vi) Propose a classification algorithm by using the features you extracted in question (iii) to classify these images into these four groups. Explain how you resolve the issue of the unbalanced dataset. [20 marks] (vii) Explain how you set up your experiments in order to have a mean and variance for the classification accuracies in each group. [7 marks] ELEC6213W1 Copyright 2021 © University of Southampton Page 4 of 4 (viii) If our dataset is very large and contains more than 4000 patients in each group, then describe an alternative approach for this classification task and explain why you would take such an approach for this large dataset instead of implementing the aforementioned steps? [18 marks] END of PAPER
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